Pain or discomfort in the pelvis that is related to the bladder. Symptoms often include a persistent urge to pee or the need to pee frequently. The cause or causes are not known. It is also called painful bladder syndrome, as the urge to urinate can feel extreme and can be accompanied by spasms and pressure. People with interstitial cystitis can have pain while urinating, while driving, and while having sex. In men, ejaculation can be painful. People with this disorder are often very depressed as a result, in part due to the pain and discomfort, and in part because it causes incredible interference in their lives.