A class of overly prescribed antidepressants which include Prozac, Zoloft, Paxil, Luvox, Celexa, Lexapro, Effexor, Serzone and Remeron. According to the Journal of Sexual Medicine, any person who has been given a prescription for an SSRI should be warned that there is a high probability of sexual side effects while on SSRI medications. In an unknown number of cases, the side effects may not resolve and could be potentially irreversible. Not to be taken lightly. Some SSRIs are given to men who experience severe premature ejaculation, due to their side effect of delaying orgasms or making them more difficult to achieve.